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Factors influencing bruising frequency include: Injection technique familiarity with the Trulicity auto-injector device may affect outcomes Anatomical injection site selection certain areas have more superficial vasculature Concurrent medication use anticoagulants significantly increase bruising likelihood Individual tissue characteristics skin thickness, subcutaneous fat distribution, and vessel fragility Injection site reactions can occur with any subcutaneously administered medication, though rates vary between different products and delivery systems

Patents prevent generic manufacturing until 2036-2040