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All groups showed a decrease in mean HbA1c by week 12, with higher doses of LY demonstrating statistically significant placebo-adjusted decreases of up to 1.56%

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When Switching to Oral GLP-1 Makes Sense Consider an oral option if you: Dislike injections Prefer a morning routine Need easier travel or storage (no refrigeration) Face insurance changes or injection site reactions Note that oral forms demand empty-stomach timing, which may challenge some schedules

This approach can support post-market safety and effectiveness studies, enable synthetic control arms for clinical research, and provide a more complete and timely view of patient journeys