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Stable isotope D9-TMA and D9-TMAO (Cambridge Isotope Laboratories, Inc.) were added to the samples as the internal standard for the TMA and TMAO quantification, respectively
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Treatment with exenatide has been shown to decrease food intake and attenuate food-related neural responses in key regions such as the insula, amygdala, putamen, and orbitofrontal cortex (van Bloemendaal et al., 2014)
An overview of the randomised controlled trials conducted in humans to evaluate the potential of GLP-1R agonists for treating NAFLD/NASH is shown in Table 1
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