Reconstituted injectable GHK-Cu: 2-8C (refrigerated): 28-30 days stable 15-25C (room temp): Degrades in 3-7 days 30C (warm): Degrades in 24-48 hours Topical serum (opened): 2-8C (refrigerated): 6-12 months 15-25C (room temp): 3-6 months 30C (warm environment): 1-3 months Raw powder (sealed): 2-8C (refrigerated): 24-36 months 15-25C (room temp): 12-24 months 30C (warm): 6-12 months Key takeaway: Every 10C increase in temperature roughly doubles the degradation rate
They work by mimicking the GLP-1 hormone, which helps improve insulin secretion, suppress glucagon release, and slow gastric emptying
GLP1-RAs currently available in Canada include semaglutide (Ozempic, Ryblesus, Wegovy), liraglutide (Victoza, Saxenda, Xultophy ), dulaglutide (Trulicity), lixisenatide (Soliqua ) and tirzepatide (Mounjaro, Zepbound)
Chronic PYY3-36 treatment promotes fat oxidation and ameliorates insulin resistance in C57BL6 mice