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Furthermore, antibodies generated in elderly individuals are often less protective than those produced by younger ones

15 Phase II trials targeting MASH have shown that treatment with SEMA 0.4 mg daily for 72 weeks resulted in more patients with liver fibrosis stage F2/F3 achieving improvement in MASH without progression of liver fibrosis (odds ratio = 6.87, 95% CI = 2.6017.63) compared to placebo

The honest framing right now: encouraging, but not yet established for this population

Treatment will depend on how large the stone is, its makeup, whether it is blocking your urinary tract and the degree of pain it is causing