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The article explains that the branded product is reviewed by the FDA for safety, efficacy and quality before it reaches market and is made under Current Good Manufacturing Practice standards, while compounded semaglutide is prepared by state-licensed 503A pharmacies following USP standards and state board regulations without that pre-market review

Differences between two factors was compared using unpaired Student's t-test, and multivariate differences were compared by one-way or repeated measures two-way ANOVA followed by Tukey's post hoc test

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