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Certain medications may also interfere with absorption and cause deficiency, in particular, medicines prescribed for heartburn, antibiotics, blood pressure medicine, cholesterol-lowering drugs, diabetes medications and antipsychotic drugs

While quite efficacious, these medications are quite expensive, with list prices ranging from $12,000 annually to roughly $16,000 annually as of March 2025, according to the September budget request from the states health and human services office

Using a 29 to 31 gauge needle, allowing the solution to reach room temperature, and injecting slowly all minimize discomfort

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