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Most commonly reported: Nausea (most common, particularly during dose escalation) Diarrhea Vomiting Constipation Abdominal discomfort These effects were generally mild to moderate in severity and tended to diminish as participants adjusted to the treatment, particularly when gradual dose escalation protocols were followed

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PubMed PMID: 1292918

doi: 10.3389/fmed.2025.1669685 30