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In rodents, semaglutide causes thyroid C-cell tumors

Glucuronidation Increases BUT Is Insufficient While glucuronidation (the other safe pathway) does increase during pregnancy: This increase in glucuronidation CANNOT compensate for the simultaneous: 33% decrease in sulfation (another safe pathway) 80% increase in oxidation to toxic NAPQI **The Result:** When both safe pathways become saturated or overwhelmed, significantly more acetaminophen is forced through the toxic CYP2E1 pathway, creating 43% more NAPQIat precisely the time when glutathione reserves are most depleted

LC, P = 0.038)

In fact, some who arent deficient in vitamin B12 choose to take advantage of this supplementation as it offers a variety of health and behavioral benefits such as increased energy, improvements in mood, and weight loss