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Multiple studies, usually done during endoscopies (EGDs) with or without colonoscopies, have shown that patients on GLP-1 receptor agonists have residual gastric contents when fasting from solids for 8 hours (70% of patients, n=10) and when fasting from solids for up to 16 hours (13.1% after 10 hr, n=84

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Its activity on MC3R and MC4R receptors has also made it a target of research in metabolic and neurobehavioral studies