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Attenuating oxidative stress and mitochondrial dysfunction Oxidative stress plays a vital role in the pathogenesis and pathophysiology of AD (181)

People taking these medicines may require dose adjustments to their existing treatments under medical supervision

2.1.1 Effects on lipid structure and on the liver The SURPASS-2, where TZP (with metformin) was compared to semaglutide (74, 88), showed adjunctive effects, such as lowering the concentrations of LDL and triglycerides and elevating the concentration of HDL

Who Should Avoid GLP-1 Medications GLP-1 treatments are generally not recommended for: Individuals with certain thyroid conditions Those with a history of specific endocrine disorders People who are pregnant or planning a pregnancy Anyone advised against it by a healthcare provider This is why eligibility screening is essential before starting treatment