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In conclusion, a therapeutic approach to IVD degeneration involving enhanced tissue repair by exogenous growth factors may be clinically important, but more research is needed to address the efficacy, duration of action, safety, and adverse effects of the growth factors administered in vivo

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Long-term weight management still depends on factors such as nutrition, exercise, sleep, stress management, and a personalized approach developed with qualified healthcare professionals

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Evaluation of production: type II collagen, aggrecan, MMP-13 (degradation enzyme), IL-1 response

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