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Diabetes 1998

The chronic low-grade inflammatory state that results, sometimes called inflammaging, creates a systemic environment that progressively impairs insulin sensitivity, disrupts lipid metabolism, and elevates cardiometabolic risk [4,5]

The profound inflammatory response to SARS-CoV-2 infection leads to the development of coagulation abnormalities 146

Mesenchymal stem cell transplantation exerts a beneficial role also in the EAE mice, the animal MS model, promoting a functional recovery ( 2+ levels by the modulation of calbindin expression, which is associated with calcium homeostasis and plays a role in the protection of dopaminergic neurons in the pathogenesis of PD (Liu et al., 2014)