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One comprehensive study on this mode is The STEP 1 trial, a randomized, double-blind study published in The New England Journal of Medicine

For someone starting at 300 lbs, this could mean 6075 lbs lost

It is important to ask a doctor about each medications side effects and to attend follow-up appointments to adjust the medication as necessary

Our findings offer comprehensive real-world evidence for the cardiovascular effectiveness of tirzepatide in clinical practice in the absence of studies with direct comparisons to semaglutide, and ahead of further evidence from the SURPASS-CVOT randomized controlled trial that compared tirzepatide against an older GLP-1 receptor agonist that is not frequently used in routine care 14,17