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19 Gene expression differences involved in O-GlcNAcylation and hexosamine biosynthesis pathway have also been detected between diabetic and nondiabetic individuals, 20 probably because multiple molecules in insulin signaling pathways can be modified by glycosylation which in turn reduces phosphorylation, leading to inhibition of insulin signaling

Wong et al., 2021

"Most of the time, we don't see all of your weight return, but some of it will, so we know that there will be lingering effects

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