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The TCF7L2 Gene: The Most Important Diabetes Gene You've Never Heard Of What it does to your GLP-1 system In 2006, scientists discovered that a variant in TCF7L2 was the strongest genetic risk factor for type 2 diabetes ever found in large population studies confirmed in hundreds of studies across multiple ethnicities, including South Asians

Phase II takes the reactive metabolites from phase II and adds another molecule to make them safer and more water-soluble for elimination

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