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Ceramide synthases in cancer therapy and chemoresistance
Synthetic antibiotics have a speedy therapeutic impact when used to treat microbial infections, but they also represent a substantial risk of gastrointestinal and renal toxicity, and microbial resistance
SOC, System organ class
To further explore the role of SNX2, we conducted all-atom molecular dynamics simulations, which revealed that the AH domain of the SNX1SNX2a complex resists membrane insertion, as the average AHmembrane distance does not decrease over the course of the simulation (Supplementary Fig
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