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However, there are significant gaps in our understanding, including determining optimal dosages for efficacy and safety, elucidating precise mechanisms of action, establishing clinical efficacy through more large-scale trials, developing personalized treatment approaches, and studying the longstanding effects of vitamin supplementation in cancer patients

One thing is abundantly clear, however

Nature 385 , 165168 (1997)

According to an analysis by Gallup, an estimated 15 million Americans say theyve used GLP-1 drugs to lose weight and a majority of people are above the age of 40.