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Since perisomatic inhibition plays an essential role in determining the time window for spike generation (Pouille and Scanziani, 2001), increased inhibition through structural rearrangements of perisomatic synapses after plasticity inducing network activity may help in ensuring precise temporal synaptic integration

A., & Wraight, C

It is very common around delicate areas like crows feet

In this light, we want to emphasize how a timely and appropriately regulated manipulation of the KEAP1-NRF2 system is crucial to develop effective and safe therapeutic treatment for neurodegenerative diseases, such as ALS, which involve an imbalance in the OS response