Mechanistically, glutaminase-mediated glutaminolysis and downstream -ketoglutarate production are essential for pro-inflammatory EV release and microglial activation during HIV-1 infection and immune activation [54, 57]
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In addition, research has shown that celiac disease and histamine intolerance may also be related in the efficacy and responsiveness of their management
Setoguchi, S., Hirooka, Y., Eshima, K., Shimokawa, H