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This analysis, updated with all GLP-1RA CVOT completed to date, supports the hypothesis that achieving HbA1c lowering with these distinct drugs might be critical for cerebrovascular events rather than MI and CV death risk reduction

Cognitive functions include memory, learning, reasoning, problem-solving, verbal fluency, and visual-spatial abilities

Statistical analysis Statistical analysis was done using one tailed students t-test for pair wise comparison or ANOVA followed by post-hoc Tukey test for multiple sample comparisons

A long, fragile peptide with no dedicated stabilization strategy does not become oral just by pressing it into a tablet