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Description

3.1.3 DON DON (6-diazo-5-oxo-l-norleucine), a glutamine analog, irreversibly inhibits various glutamine utilization enzymes, such as glutaminase and glutamine synthetase, by forming covalent bonds with nucleophilic residues on the active site of the enzyme (Rajagopalan and DeBerardinis, 2011

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Pflgers Archiv - Eur J Physiol (2016) 468(10):176577

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doi: 10.1007/s10803-004-5283-1 69

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The study provided insight into how Sema influences energy balance in controlled conditions

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