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Cryosections staining and microscopy Hematoxylin and eosin (H&E) and immunofluorescence of tissues were performed on snap-frozen tissue samples in O.C.T

4.4 Mechanistic exploration of repurposed anti-diabetic drugs Preclinical data reporting the neuroprotective effects of drugs such as GLP-1 receptor agonists (e.g., Liraglutide) and SGLT2 inhibitors raise the possibility that their benefits extend beyond glycemic control to potentially encompass the inhibition of ferroptosis (Xie et al., 2023)

23 These reports and others 21, 72, 73 characterize the LS as a brain region critically involved in coordinating the activity of multiple reward centers and reinforce its importance in cocaine reward

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