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The combination of anticancer therapies with GPX4 inhibitors eliminated senescent tumour cells in models of melanoma, prostate and ovarian cancer

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described an EC50 of DPDPE on DOR = 5.2 1.2 nM) (Suh & Tseng, 1990)

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However, researchers estimate that the lethal dose of GHK-Cu would be about 330 mg/kg of body weight, which is over 300 times larger than its known effective dose

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