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Lancet Diabetes Endocrinol (2017) 5(5):34154

"We set out to make a molecule that could help patients achieve substantial A1C reduction and weight loss," Custer said

Phase I metabolism for dihexa Phase I metabolism of dihexa, which was determined using pooled male rat liver microsomes, was found to be veiy low with an average intrinsic clearance (Clin t ) of 2.72 7 / 3 4 and an average half-life of 509.4 minutes