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A Mayo Clinic study offers a potential answer by identifying a distinct biological subtype of obesity that responds especially well to tirzepatide, a medication that mimics two naturally occurring hormones involved in appetite and blood sugar regulation, moving the field closer to precision medicine for obesity

J Invest Dermatol 136(1):339342 Acknowledgements The authors are grateful to Alexandra Fischer for administrative support

38% PDC 80%), but nearly half of weekly-injectable users still fell below the adherence threshold associated with clinically meaningful HbA1c reduction

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