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Our bodies do not make vitamin b12, we consume it in our diet

Patients should be reviewed 812 weeks after commencing treatment to assess: Symptomatic improvement, particularly resolution of fatigue and neurological symptoms Haematological response (normalisation of haemoglobin and mean cell volume) Reticulocyte count typically rises within one week, indicating bone marrow response Repeat serum B12 testing is generally not useful after starting parenteral therapy, as levels remain elevated for months

B12-related acne typically develops within one to four weeks of initiating supplementation or receiving injections

Proper use assures appropriate reimbursement and reduces claim denials