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Pickart 2015 BioMed Res Int sequenced by Affymetrix chip the effects of 10 nM GHK-Cu on human fibroblasts after 24h: 4192 significantly modulated genes, including activation of DNA repair programmes (NBN, BRCA1), regeneration (collagens, elastin, integrins), antioxidant defence (glutathione peroxidase, SOD, peroxiredoxins) and anti-inflammatory modulation (reduction of TNF-alpha, IL-6, IL-8)

Although vitamin B12 is water-soluble and excess amounts are typically excreted in the urine, the body still stores significant quantities (primarily in the liver) with its levels continuously regulated