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GST is able specifically to bind to GSH or GSH analogs via the G-site, which catalyzes the interaction between GST amino-acid residues with GSH sulfhydryl and conventional electrophilic substances at the H-sites to promote catalytic action

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Additionally, we examined the effects on hepatic oxidative stress, serumiron metabolism-related indicators, and the mRNA expression of tissueiron metabolism-related indicators

Consistent with a role for GPx1 in promoting the progression (of some forms) - of renal carcinoma, it was found that short hairpin RNA-mediated suppression of GPx1 expression decreased cell growth and colony formation in a number of renal cancer cell lines grown in culture [136]