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Oxidized phospholipids in Doxorubicin-induced cardiotoxicity

Interestingly, CD36 overexpression in SUM-159 cells but not in MCF-7 cells increases the enrichment score of the ferroptosis pathway in conjunction with the upregulation of iron utilization, reactive oxygen species pathway, and the downregulation of ferroptosis suppressor pathway, such as CoQ10, thioredoxin, and BH4

doi: 10.1002/ptr.6537 47

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