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This reflects a key limitation: GLP-1 medications can reduce appetite and support weight loss, but they do not by themselves establish a long-term metabolic framework for maintaining that loss

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Less food means fewer opportunities to absorb B12 from dietary sources

Last reviewed: May 30, 2026 Last updated: May 30, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations