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The dura mater, intracranial vessels, trigeminal nerve perivascular fibers, trigeminal ganglion (TG), caudal subnucleus of the trigeminal nucleus caudalis (TNC), hypothalamus, and cerebral cortex are all part of the system (Charles and Brennan, 2010)

With regard to kidney protection, in the doxorubicin (DOX) induced acute nephrotoxicity rat models, it was found that the treatment with L-theanine could attenuate the decrease of creatinine clearance, inhibit the production of lipid peroxidation in the kidney, and inhibit the reduction of glutathione content and SOD activity after DOX administration (90)

Elevated YAP nuclear levels have been detected in CAFs within adenoma and carcinoma lesions in mice as well as in stromal fibroblasts of human breast cancer

Eating small, frequent meals with balanced macronutrients helps stabilize blood sugar and prevents rapid shifts in blood pressure