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The primary endpoint for this study was the number of live offspring per round of confirmed mating, which was determined by the presence of a vaginal plug as described above, and the total number of live offspring for each cohort, with n = 10 animals per group

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As one pharmaceutical review noted, "the activation of pro-migratory signals and pro-angiogenic factors by BPC-157 is a double-edged sword." No studies have proven that BPC-157 causes cancer, but the biological plausibility of this concern cannot be dismissed