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When the expression of 44 pro-apoptotic genes was assessed in the postmortem hippocampus, 19 of those genes were significantly upregulated in BD, which was unrelated to the exposure to mood stabilizers [56]

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531 More accurate studies of morphology of astrocytes in aged mice in situ using intracellular injections of fluorescent dye Alexa Fluor 594 with subsequent two-photon imaging and 3D reconstruction identified a substantial reduction of astrocytic size and complexity with particular degradation of perisynaptic leaflets (Fig

It is frequently used in anti-aging and metabolic research related to GH/IGF-1 axis regulation