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They were approved for therapy by the FDA and EMA in 2014, although albiglutide was withdrawn from the market in 2018 for economic reasons

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This biased agonism means tirzepatide can enhance insulin secretion more effectively than semaglutide, particularly in people whose GLP-1 signaling is partially blunted

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These findings raise the question as to whether SARS-CoV-2 can trigger this metabolic disease

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GLP-1R agonists may serve as adjunctive therapies for cognitive impairments related to depression, particularly in women, as evidenced by exendin-4 enhancing cognitive performance in female mice (Trammell et al

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