481 GuptaSAggarwalSSeeDStarrA
GLP-1RA Therapy as a Chronic Flux Perturbation System-Level Energy Flux Reorganization Under Weight Loss Therapy Most weight-loss interventionsincluding exercise [49], calorie restriction [50], cold exposure [51], and selected antidiabetic agents [10, 52]ultimately increase reliance on FAO, which supplies acetyl-CoA to sustain tricarboxylic acid (TCA) cycle activity and electron transport chain (ETC)coupled adenosine triphosphate (ATP) production
Parenteral administration of minute amounts of endotoxins to humans elicits an inflammatory reaction typical of SIRS (fever or hypothermia, tachycardia, hyperpnea, leukocytosis, and hypotension), whereas larger amounts of administered endotoxins typically produce sepsis and shock [66, 67]
Asia Pacific Journal of Clinical Nutrition, 17 Suppl 1 , 167-168