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doi: 10.1155/2021/6665563

While APR-246 treatment did cause dose-dependent increase in caspase activity, this appeared to be independent of p53-expression (Fig

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Below are the factors which need to be checked in order to diagnose these moles Any changes in the colour, shape, size and structure of the mole If the mole develops when you are in your 40s If a particular mole appears to be different from all the other moles that you might have It has the characteristics of the ABCD guideline which is Asymmetry, Border irregularity, Colour variation and Diameter greater than 6 mm If the mole is bleeding and has an itchy and crusty surface