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Hypothalamic anorexigenic signaling pathways (leptin, amylin, and proopiomelanocortin) are semaglutide (GLP-1 analog) targets in obesity control in mice

2.3 Categories of underexplored peptidereceptor systems To provide a structured framework for subsequent sections, the major categories of underexplored peptidereceptor systems examined in this review are summarized in Table 1, which is cited here to contextualize the scope and rationale of inclusion

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Effects of the Novel (Pro 3 )GIP Antagonist and Exendin(9-39)Amide on GIP- and GLP-1 Induced Cyclic AMP Generation, Insulin Secretion and Postprandial Insulin Release in Obese Diabetic ( Ob/Ob ) Mice: Evidence that GIP Is the Major Physiological Incretin