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The consumption of glutamine by the cancer cells in clear cell renal cell carcinoma (ccRCC) results in the local deprivation of extracellular glutamine This, in turn, triggers the release of IL-23 by cancer-infiltrating macrophages via the activation of hypoxia-inducible factor 1 (HIF1) [71]

Prognostically important EEG coma patterns in diffuse anoxic and traumatic encephalopathies in adults

These findings are consistent with an emerging body of literature suggesting that GLP-1RAs, influence central nervous system pathways involved in sleep regulation

EC 50 -values were determined from the concentration-response curves using a three-parameter logistic equation