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With meals: Take Contrave with food, but avoid high-fat meals , which can increase side effect risk

The implicit message seemed to be: Weight loss is a nicety, not a medical condition linked to type 2 diabetes, heart disease, high blood pressure, stroke, a host of cancers, anxiety, depression, and polycystic ovary syndrome, to name a few

"cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity." J Clin Invest

Then there were these other small molecules that didn't have safety problems associated with them, so that meant that the entire field of obesity and big pharma died out for some time