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Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapyA consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes

These adapter proteins become phosphorylated themselves, creating more docking sites that recruit and start downstream signaling molecules

The hazard ratios (HRs) and confidence intervals (CIs) were calculated using a stratified Cox proportional hazards model in which treatment was considered a fixed effect and trial-level cardiovascular risk as the stratification factor

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