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Discuss with your provider whether your testosterone regimen might benefit from dose adjustments as your weight and appetite change on GLP-1 therapy, ensuring hormone replacement remains appropriate throughout your weight loss journey

Markers for significance and sample sizes are shown in figure legends

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Physicians specifically screen for pancreatitis history, personal or family history of medullary thyroid cancer, and multiple endocrine neoplasia type 2, as semaglutide carries contraindications in these populations