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Intravenous, or infusion, therapy is an alternative or addition to oral treatment

Pevec D, Novinscak T, Brcic L, et al

Tan HC, Dampil OA, Marquez MM

Conclusions Changes in intra-portal insulin levels play an intricate yet permissive role in the regulation of the GH/IGF-I axis by either stimulating or suppressing hepatic GH sensitivity and hepatic IGF-I generation, probably via an insulin-mediated regulation of the hepatic GHR expression