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381:841-851 [PubMed: 31185157] 381

124,316 Duchenne muscular dystrophy Duchenne muscular dystrophy (named after Guillaume-Benjamin-Amand Duchenne de Boulogne who provided early and comprehensive description of clinical presentation and histopathology of this disorder 317 ) is an X-linked recessive neuromuscular disorder caused by mutations in the DMD gene that encodes the protein dystrophin

Most patients report body aches lasting 2-4 weeks, typically appearing during dose escalation or the first month of therapy

The chatter online is sprawling, often filled with speculation rather than hard data, making it difficult for serious researchers to separate signal from noise