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It is classically characterized as an allergic disease associated with type 2 inflammation [243]
Among patients with T2D who had a prior history of CUD, semaglutide was associated with a lower risk for recurrent CUD diagnosis (medical encounters for CUD diagnosis) compared with non-GLP-1RA anti-diabetes medications for a 12-month follow-up period (13.7% vs
In an obese mouse model of diabetes, GLP-1 was shown to reduce macrophage infiltration and directly inhibit inflammatory pathways in adipocytes and adipose tissue macrophages (79)
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