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[51] These are not edge cases

The relatively low discontinuation rate despite side effects affecting 39-44% of users underscores an important point: most adverse events are tolerable and manageable, not severe enough to warrant stopping therapy

These patients, who collectively account for 25-30 percent of all people with major depression disorder, are precisely the ones most in need of effective pharmacological interventions, said Rasgon, who performed the bulk of the advanced data analysis for the study