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Rg1 can suppress inflammatory responses by blocking essential inflammatory pathways such as NF-B, MAPK, JAK2/STAT3, and TLR4/NF-B, leading to the production and release of decreased inflammatory mediators (Zhou et al., 2025)

After the development of IDA, these female rats were mated with male rats and allowed to become pregnant, simulating the gestational anemia state following IDA caused by poor nutritional status in clinical practice

In addition, in cultured cells, overexpression or underexpression of GCH1 made cancer cells correspondingly resistant or sensitized to ferroptosis