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Larazotide prevents the redistribution of ZO-1, occludin, and claudin proteins that occurs during zonulin-mediated tight junction opening

But, as Dr

Fontana-Masson or Warthin-Starry stain for melanin and immunohistochemical studies with various melanocytic markers such as S-100 protein, Mart1/MelanA, MITF-1, and HMB-45 are helpful in highlighting the differences in melanin content as well as the presence and density of melanocytes between normal and lesional skin samples (Fig