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The continuous hyperglycemia can induce target organ damage (TOD) by increasing the risk of panvascular disease, including microvascular disease (such as diabetic retinopathy, nephropathy and neuropathy), and atherosclerotic macrovascular disease (cardiovascular, cerebrovascular, and other peripheral vascular diseases)

Chen JJ, Mollan SP (2025) Treatment and monitoring of idiopathic intracranial hypertension

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- Produce collagen, the connective tissue that supports our organs and forms the bones, skin, ligaments, tendons, and joints