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GLP-1 receptor agonists are not recommended to be used during pregnancy, and so we can assume that the vast majority, if not all, of patients had stopped use either before or soon after conception, Nau told Healio

Other drugs, such as monoamine oxidase B (MAO-B) inhibitors (e.g., rasagiline, safinamide, selegiline) or catechol-O-methyltransferase (COMT) inhibitors (e.g., entacapone, tolcapone), may also be used to improve dopamine levels, although sometimes symptoms may persist or worsen even with optimized dopaminergic therapy (Pardo-Moreno et al., 2023